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Dabigatran Etexilate versus Warfarin in Management of Non-Valvular Atrial Fibrillation in UK Context: Quantitative Benefit-Harm and Economic Analyses
BMJ 343:d6333, Pink, J.,et al, 2011
See this aricle in Pubmed

Article Abstract
This analysis supports regulatory decisions that dabigatran offers a positive benefit to harm ratio when compared with warfarin. However, no subgroup for which dabigatran 110 mg offered any clinical or economic advantage over 150 mg was identified. High dose dabigatran will be cost effective only for patients at increased risk of stroke or for whom international normalized ratio is likely to be less well controlled.
 
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anticoagulant,treatment
atrial fibrillation
cerebrovascular accident,prevention of
cost
cost effectiveness
coumarin
dabigatran
factor Xa inhibitor
risk-benefit assessment
treatment of neurologic disorder

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